..  docs/source/tasks/asdas.rst

..  Copyright (C) 2012, University of Cambridge, Department of Psychiatry.
    Created by Rudolf Cardinal (rnc1001@cam.ac.uk).
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.. _asdas:

Ankylosing Spondylitis Disease Activity Score (ASDAS)
-----------------------------------------------------

.. include:: include_data_collection_plus_local_upgrade.rst

Four numerical rating scales rated 0-10 and a measure of inflammation (either
C-reactive protein, CRP, or erythrocyte sedimentation rate, ESR).

Each question is weighted:

.. code-block:: none

  ASDAS-CRP =
                0.12 × back pain +
                0.06 × duration of morning stiffness +
                0.11 × patient global +
                0.07 × peripheral pain/swelling +
                0.58 × ln(CRP + 1)

    ... where CRP is measured in mg/L

  ASDAS-ESR =
                0.08 x back pain +
                0.07 x duration of morning stiffness +
                0.11 x patient global +
                0.09 x peripheral pain/swelling +
                0.29 x √(ESR)

    ... where ESR is measured in mm/h


Intellectual property rights
~~~~~~~~~~~~~~~~~~~~~~~~~~~~

**TO BE ESTABLISHED.** Original paper (Lukas et al. 2009) is copyright 2009 BMJ
Publishing Group and European League Against Rheumatism, but status of task
itself less clear.

Braun et al. (2014, p. S-100) state "Another major difference between BASDAI
and ASDAS is that the latter is entirely in the public domain..."; the last
author (van der Heijde) is also the last author of the original article.


History
~~~~~~~

- Lukas C, Landewé R, Sieper J, Dougados M, Davis J, Braun J, van der Linden S,
  van der Heijde D (2009).
  Development of an ASAS-endorsed disease activity score (ASDAS) in patients
  with ankylosing spondylitis.
  *Ann Rheum Dis.* 68: 18-24.
  https://www.ncbi.nlm.nih.gov/pubmed/18625618

For copyright status, see also:

- Braun J, Kiltz U, Baraliakos X, van der Heijde D (2014).
  Optimisation of rheumatology assessments - the actual situation in axial
  spondyloarthritis including ankylosing spondylitis.
  *Clin Exp Rheumatol.* 32(5 Suppl 85): S96-S104.
  https://www.ncbi.nlm.nih.gov/pubmed/25365096


Source
~~~~~~

- https://www.asas-group.org/clinical-instruments/asdas-calculator/
- http://oml.eular.org/oml_search_results_details.cfm?id=31&action=All%20information